Jie Jack Li's Blockbuster Drugs: The Rise and Decline of the PDF

By Jie Jack Li

For the world's greatest prescription drug brands, the previous few years were a harrowing time. lately, Pfizer's Lipitor, GlaxoSmithKline's Advair, AstraZeneca's Seroquel, and Sanofi-Aventis and Bristol-Myers Squibb's Plavix all got here off patent within the the most important U.S. marketplace. This so-called "patent cliff" intended 1000's of billions of greenbacks in misplaced profit and has pharmaceutical builders scrambling to create new medicinal drugs and litigating to increase present patent protections.

Having spent such a lot of his occupation in drug discovery in "big pharma," Dr. Li now provides an insider's account of ways the drug ascended to its plateau and explores the character of the turmoil it faces within the coming years. He starts with a survey of the panorama sooner than "blockbuster drugs," and proceeds to explain how these medicinal drugs have been chanced on and consequently turned crucial to the enterprise types of huge pharmaceutical businesses. for instance, in early Eighties, Tagamet, the 1st "blockbuster drug," remodeled a minor Philadelphia-based drug maker named SmithKline & French into the world's ninth-largest pharmaceutical corporation by way of revenues. The undertaking that added Tagamet used to be approximately terminated a number of instances simply because study efforts all started in 1964 produced no obvious effects in the first 11 years. comparable tales accompany the invention and improvement of now-ubiquitous prescribed drugs, between them Claritin, Prilosec, Nexium, Plavix, and Ambien.

These tales, and the points of the pharmaceutical that they exhibit, can educate us priceless classes and display many an important facets in regards to the destiny panorama of drug discovery. As constantly, Dr. Li writes in a readable type and intersperses interesting tales of medical discovery with attractive human drama.

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Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry by Jie Jack Li


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